Volume 5, Issue 4, December 2019, Page: 230-233
Congenital Cytomegalovirus Infection Presenting as Pneumonia with Respiratory Distress and Thrombocytopenia
Nipun Shrestha, Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal
Bhabuk Sharma Majagaiya, Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal
Dhruba Shrestha, Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal
Received: Aug. 12, 2019;       Accepted: Sep. 6, 2019;       Published: Oct. 23, 2019
DOI: 10.11648/j.ajp.20190504.21      View  64      Downloads  36
Abstract
Human Cytomegalovirus (CMV) is a member of Herpes viridae family, that affects most of the human population at some stage of live and is the most common congenital infection causing sensorineural hearing loss and neurodevelopmental delay in newborn. CMV infection may be acquired in a newborn congenitally or after delivery, but except for the congenital infection, other mode of infection rarely result in significant symptoms or sequel in them. Clinical findings of congenital CMV infection include IUGR, hydrops, generalized petechiae, purpura, thrombocytopenia, jaundice, hepatosplenomegaly, pneumonitis, microcephaly, periventricular calcifications, seizures, chorioretinitis, sensorineural hearing loss, bone abnormalities, abnormal dentition, and hypocalcified enamel. Here we present a case of congenital CMV infection who presented with Pneumonia with Respiratory distress and thrombocytopenia. A single, live, term, female child delivered at home developed low grade fever, cough and increased oral secretion at 28 day of life and was initially diagnosed as Pneumonia with respiratory distress with thrombocytopenia. Mother and child, both were investigated for TORCH infection which came out to be positive for CMV infection (child’s serum CMV Ab IgM 94 U/ml). Her CMV Viral Load Real Time PCR tested positive with 56380 copies/ml.
Keywords
Human Cytomegalovirus, Herpes Viridae, Thrombocytopenia, TORCH
To cite this article
Nipun Shrestha, Bhabuk Sharma Majagaiya, Dhruba Shrestha, Congenital Cytomegalovirus Infection Presenting as Pneumonia with Respiratory Distress and Thrombocytopenia, American Journal of Pediatrics. Vol. 5, No. 4, 2019, pp. 230-233. doi: 10.11648/j.ajp.20190504.21
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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