Volume 5, Issue 4, December 2019, Page: 191-195
Antibiotic Resistance Pattern in Children with UTI: A Study in a Tertiary Care Hospital, Dhaka, Bangladesh
Md. Atiqul Islam, Department of Paediatric Infectious Diseases and Community Paediatrics, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh
Sheuly Begum, Department of Gynaeocology &Obstetrics, Enam Medical College, Savar, Dhaka, Bangladesh
Salina Shaheen Parul, Bio-chemistry Department, Sylhet MAG Osmani Medical College, Sylhet, Bangladesh
A. K. M. Tajuddin Bhuyian, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh
Md. Tazul Islam, 250 Bedded General Hospital, Jamalpur, Bangladesh
Md. Kariul Islam, International Online Journal Hub (IOJH), Dhaka, Bangladesh
Received: Jun. 19, 2019;       Accepted: Jul. 31, 2019;       Published: Sep. 18, 2019
DOI: 10.11648/j.ajp.20190504.14      View  38      Downloads  14
Abstract
Urinary tract infection (UTI) is one of the most common pediatric infections. It distresses the child, concerns the parents, and may cause permanent kidney damage. Occurrences of a first-time symptomatic UTI are highest in boys and girls during the first year of life and markedly decrease after that. Febrile infants younger than 2 months constitute an important subset of children who may present with fever without a localizing source. For resistance knowledge of etiology pathogens of UTIs and their antimicrobial resistance patterns in specific geographical location may help clinicians in choosing the appropriate antimicrobial. Our aim was to assess bacteriological profile and antibiotic resistance pattern in pediatric UTI. A cross sectional study was conducted at Dhaka Shishu Hospital during the period from Feb 2016 to Aug 2016. A total of 147 culture positive UTI patient were considered for analysis. Colony counts for these samples were identified, and the profile of antibiotic resistance was identified. Here, samples with a colony count of ≥105 CFU/mL bacteria were considered positive. A total 147 culture positive UTI patients were enrolled. Here, Escherichia coli (E-coli) was found as the most prevalent isolates 103 (70%) followed by Klebsiella spp. 13.6%, Pseudomonas 5.44%, Enterobacter spp 3.40%, Staphylococcus Aureus 3.40%, Proteus 2.72% and Enterococcus 1.36%. Twelve (12) antimicrobial agents were used for antimicrobial susceptibility testing. The most resistant drugs we found were Colistin (CL) (94.55%), followed by Cefradine (79.59%), Co-trimoxazole (SXT) (69.39%), Nalidixic acid (NA) (66.67%) and Ceftazidime (CTM) (48.98%). None of the drug found was 100% resistance against urinary pathogens. Antimicrobial drug resistance is decreasing among urinary pathogens. We suggest that, empirical antibiotic selection should be based on knowledge of the local prevalence of bacterial organism and their antibiotic resistance in a specific area rather than on universal or even national guidelines.
Keywords
UTI, Antibiotic Resistance, Urinary Pathogens
To cite this article
Md. Atiqul Islam, Sheuly Begum, Salina Shaheen Parul, A. K. M. Tajuddin Bhuyian, Md. Tazul Islam, Md. Kariul Islam, Antibiotic Resistance Pattern in Children with UTI: A Study in a Tertiary Care Hospital, Dhaka, Bangladesh, American Journal of Pediatrics. Vol. 5, No. 4, 2019, pp. 191-195. doi: 10.11648/j.ajp.20190504.14
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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