American Journal of Pediatrics

Volume 5, Issue 2, June 2019

  • Application of Hemoadsorption in Neonatal and Pediatric Hyperinflammatory States: A Case Series

    Leonardo Milella, Maria Teresa Ficarella, Gerolmina Calabrese, Michele Sisto, Rita Luana Grieco, Paola Moliterni, Pasquale Raimondo, Fabiana Cito, Vito Bellino, Antonio Ranieri, Mario Giordano

    Issue: Volume 5, Issue 2, June 2019
    Pages: 34-42
    Received: Feb. 20, 2019
    Accepted: Apr. 09, 2019
    Published: May 06, 2019
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    Abstract: Objective: Extracorporeal blood purification therapies are increasingly applied in the field of intensive care medicine. Compared to filtration-based methods mainly used for renal replacement therapy, newest adsorptive approaches have shown to specifically target the inflammatory cascade by the effective removal of relevant mediators. In the neonat... Show More
  • Parental Satisfaction on Multiple Daily Injections, Insulin Pump and Flexible Multiple Daily Injections Used for Children with Type 1 Diabetes Mellitus

    Anutosh Shee, Sarah Prior, Nicole Reeves, Maria Smith, Sharon Luccisano

    Issue: Volume 5, Issue 2, June 2019
    Pages: 43-50
    Received: Dec. 16, 2018
    Accepted: Jan. 28, 2019
    Published: May 10, 2019
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    Abstract: Aims: This study aims to identify differences in parental satisfaction between three distinct types of intensive insulin therapies used for children with type 1 diabetes (T1D) namely multiple daily injection (MDI), continuous subcutaneous insulin infusion (CSII) and flexible multiple daily injection (fMDI). Materials and Methods: Data was collected... Show More
  • Grape Seed Proanthocyanidin Extract Adjusts NeuN/GFAP in a Murine Model of Neonatal Hypoxic-ischemic Brain Injury

    Li Luo, Xing Tu, Xuexia Zhang, Jing Liu, Yilin Liu, Wenyan Zhao, Ke Niu, Junhua Yang, Guoying Li, Mengxia Wang

    Issue: Volume 5, Issue 2, June 2019
    Pages: 51-55
    Received: Mar. 20, 2019
    Accepted: Apr. 22, 2019
    Published: May 10, 2019
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    Abstract: Objective: To investigate the neuroprotective effects of grape seed proanthocyanidin extract(GSPE)on a model of neonatal hypoxic ischemic encephalopathy (HIE), we investigated the changes in neuronal cells and astrocytes after pre-treatment with GSPE. Methods: Seven-day-old pups were randomly divided into sham, HI, and GSPE+HI groups. The HIE model... Show More
  • Drug-Induced Liver Diseases in Children and Adolescents

    Sergey Postnikov, Nataliya Teplova, Aleksey Ermilin, Anna Gratzhianskaya, Marya Kostyleva

    Issue: Volume 5, Issue 2, June 2019
    Pages: 56-63
    Received: Mar. 09, 2019
    Accepted: Apr. 22, 2019
    Published: May 20, 2019
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    Abstract: Many drugs (now it’s known more than 1200) are associated with hepatic side effects. Children (especially newborns and infants) are unique population with specific characteristics of absorption, metabolism and elimination of drugs that can predispose to hepatotoxicity. Aim of this review is to estimate risk factors of hepatotoxicity related to the ... Show More
  • The Effect of Bladder and Lumbar Stimulation Technique for Collection of Urine in Newborns

    Rajbanshi Mamta, Karn Basant Kumar, Yadav Upendra, Shah Sunita, Yadav Satish

    Issue: Volume 5, Issue 2, June 2019
    Pages: 64-69
    Received: Apr. 11, 2019
    Accepted: May 10, 2019
    Published: Jun. 04, 2019
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    Abstract: Background: Sign and symptoms of urinary tract infections (UTI) are not specific in infants and young children, fever being the commonest sign. Therefore, collecting urine samples for culture is required to diagnose or exclude UTI. Obtaining a clean catch urine sample in neonates and infants is a great challenge as it is unpredictable, time consumi... Show More
  • Burden of Malaria in Children Presenting with Anaemia at Ola During’s Children’s Hospital in Freetown Sierra Leone

    Yaguo Ide Lucy Eberechukwu, Lannes Namusa Susan Kamara

    Issue: Volume 5, Issue 2, June 2019
    Pages: 70-73
    Received: Mar. 11, 2019
    Accepted: May 20, 2019
    Published: Jun. 13, 2019
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    Abstract: Malaria is a serious public health problem in sub-Saharan Africa, where it affects entire populations especially children. Indeed over 80% of the worldwide cases of malaria occur in Africa. Anemia secondary to malaria is much more common in younger children, with high mortality rates. Malaria is endemic throughout Sierra Leone and it is often assoc... Show More
  • Prediction of Upper Limits of Normal Values of Anti Streptolysin ‘O’ Titres in Normal Healthy School Going Children of 6–16 Years

    Chikkanarasa Reddy Parthihally Sanjeevaiah, Mohammedmusthaq Ahamed, Basavarajaiah Doddagangavadi Mariyappa

    Issue: Volume 5, Issue 2, June 2019
    Pages: 74-77
    Received: Feb. 27, 2019
    Accepted: Apr. 11, 2019
    Published: Jun. 20, 2019
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    Abstract: Antistreptolysin O test, an internationally gold standard test is widely used in detection of group A streptococcal infections and their sequelae at global level. An observational study was conducted at Bengaluru city during 2015-16. A total 454 children were randomly selected from the different schools in Bangalore city. As per the results, the se... Show More